NATURE ELECTRONICS Fifty years after the term brain–computer interface was coined, the neurotechnology is being pursued by an array of start-up companies using a variety of different technologies. But the path to clinical and commercial success remains uncertain.

NATURE When the makers of electronic implants abandon their projects, people who rely on the devices have everything to lose.

The Pharmaceutical Journal Although current COVID-19 vaccines have been hugely effective at reducing serious disease and death, we need to prevent transmission to truly bring the pandemic under control, and that is where it is hoped mucosal vaccines will come in

CRUK Forty years ago, hints of a new component of the immune system caused a stir. As the initial controversy turned into therapeutic promise, the importance of translating this research for the treatment of cancer became very clear. Here, we chart the story of gamma delta T cells from discovery to clinical trials…

NATURE OUTLOOK Despite its chequered past, deep-brain electrical stimulation is finally showing some signs of success.

NATURE A measure of last resort got a major workout during the pandemic. Scientists are now trying to determine whether the benefits outweighed the potential damage to public trust.

NATURE OUTLOOK The hundreds of receptors that give us our sense of smell have been found to have important roles in other parts of the body, and the prospect of targeting them with drugs is growing.

NATURE Implants are becoming more sophisticated — and are attracting commercial interest.

NATURE OUTLOOK The global effort to eliminate the disease depends heavily on blocking the most common mode of viral infection

NATURE OUTLOOK If biological ageing can be slowed, halted or rewound, are the machine-learning algorithms the best way to measure it? Some experts are unconvinced.

NATURE OUTLOOK Several major organizations are calling for radical reforms to improve oral health. What’s holding them up?

NATURE OUTLOOK The ability to develop animals that have human organs could save the lives of people waiting for transplants, but ethical issues still need to be faced.

NATURE OUTLOOK Trials to replace the pancreatic β cells that are destroyed by this autoimmune disease are raising hopes of a cure. By Liam Drew

THE INDEPENDENT When Catherine Impey started a radical newspaper that challenged Victorian readers to think about race, her ideas were far ahead of her time. Liam Drew takes a closer look

Unpublished Coda to article in THE INDEPENDENT Impey never again operated at the level of national or international politics or journalism. But she forever stood up for the causes she believed in

FUTURA How to map 37 trillion cells. Founded and led by two pioneering female scientists, the Human Cell Atlass marries technical innovation with open science and collaborative spirit..

NATURE OUTLOOK To strike a ball moving at lightning speeds in baseball, tennis and cricket, athletes and coaches are increasingly embracing training techniques involving virtual reality.

SIMONS FOUNDATION The most comprehensive wiring map to date of the fruit fly brain has transformed the field of neuroscience, identifying new cell types and reconfiguring circuit models. Are neuroscientists now ready to tackle the mouse brain?

FUTURA

If a microscopic film crew could make a movie of the cellular landscape of your brain, aside from the blood coursing through the brain’s 650 km of blood vessels, most cells would be largely motionless except microglia. They would be the hyperkinetic dancing stars of this production.

NATURE OUTLOOK Migraines are often associated with colourful visual disturbances called auras, but many mysteries remain about how they fit into the wider biology of the syndrome.